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Vixea Manplus concentration of SHBG. Example: For diabetes, SHBG concentrations are low. During pregnancy the SHBG concentrations are high, so the concentrations of free This are very low. During pregnancy SHBG concentrations increase up to 10 times their baseline value This increase is significant as early Manplus as 10 weeks and reaches its maximum at 25 30 weeks of pregnancy, then the SHBG concentrations return to basal values one week after delivery. It has been proposed that this increase would have the role of limiting the transfer of This from maternal plasma to the fetus and protecting it from an excess of .

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